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She is also a supporter of various charities and an activist for Down syndrome awareness.
Dern was born in Los Angeles, California, the daughter of actors Diane Ladd and Bruce Dern, and great-granddaughter of former Utah governor and Secretary of War, George Dern; Dern was conceived while her parents were filming The Wild Angels.
In 1998, Dern co-starred in Jodie Foster's film The Baby Dance.
While dating Thornton in 1999, she was cast as his love interest in his film Daddy and Them, which also includes Diane Ladd.
That same year, Clint Eastwood contacted the actress for his film A Perfect World.
However, Laura Dern claims the emancipation was done solely for professional reasons and that both of her parents supported her in this.Between 19, Dern gained critical acclaim for roles in Mask, Blue Velvet, and Wild at Heart.Dern's starring role in Blue Velvet was a breakthrough though her next notable film, Wild at Heart, took almost four years to be released.She received international recognition with her role in the adventure film Jurassic Park (1993).
In 1997, Dern guest-starred in the "Puppy Episode" of the sitcom Ellen, in which Ellen De Generes publicly came out.Dern also appeared in Joe Johnston's film October Sky.